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Clinical trials across various autoimmune diseases, such as SLE, RA, type 1 diabetes, and Primary Sjgren's Syndrome, have demonstrated that Low-dose IL-2 can safely and effectively induce stable Treg cell proliferation and restore immune balance, leading to improved disease activity (266271)
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Either way, these studies clearly indicate that NRF2 is critical in maintaining the neurogenic capacity of NSCs, particularly in the presence of increased oxidative stress
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